Treatment Modalities of Cytokine Storm in Covid-19

This publication delves into the management of the cytokine storm linked to COVID-19, which is an uncontrolled release of cytokines. Although the pathophysiology is complicated, it involves loss of both local and systemic regulatory control over the production of proinammatory cytokines, leading to morbidity and mortality of COVID-19 cases. In this study, we summarize previous ndings and analyze data from other studies to provide a comprehensive understanding of the treatment roles, while also highlighting the efcacy and mechanisms of action of glucocorticoids, Anakinra and Tocilizumab.