Figure S9 from BBT-176, a Novel Fourth-Generation Tyrosine Kinase Inhibitor for Osimertinib-Resistant Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer

Supplementary Figure 9. Circulating tumor DNA analysis data from Case 2. A, Allelic configuration of T790M (red), L792H (green) and C797S (blue). B, Serial changes in allelic frequency of mutations detected in blood. C, Concentration-response curves and IC50 values of BBT-176 for EGFR 19Del/T790M/L792H mutant kinase.