Key points are not available for this paper at this time.
Introduction: Dengue fever (DF) is one of the most common and the most important vector-borne diseases caused by arboviruses with a significant mortality and morbidity. The incidence of DF is increasing over the years. This study aims to map the clinical features of the disease. Materials and Methods: This prospective, observational study was done among adult patients at a tertiary care medical college hospital. Two thousand three hundred and fourteen patients were studied and analyzed. All patients who were nonstructural protein 1 (NS1) antigen/IgM dengue positive were included in the study. Clinical features, hematological, and biochemical parameters were noted. Results: In the 2314 patients studied, body pain was the major symptom (35.4%) followed by headache (33.5%), fever (24.5%), nausea (16.9%), rash (16.6%), eye pain (16.2%), vomiting (12.1%), joint pain (10.2%), diarrhea (6.1%), anorexia (4.7%), cough (3.7%), lethargy (2.2%), and sore throat (1.2%). Hemorrhagic manifestations were noted in 263 patients (11.36%), of which the most common was epistaxis (50.1%) followed by purpura/ecchymosis (8.7%), hematemesis (6.8%), bleeding gums (6.8%), blood in stool (6.4%), hematuria (2.6%), and vaginal bleeding (0.4%). Patients positive for dengue NS1 were 1709 (73.9%), dengue IgM were 154 (6.66%), and both dengue NS1 and IgM were 743 (32.1%) patients. The mortality rate was 0.8%. Of 2314 patients, 29.52% had severe thrombocytopenia (<20,000/mm 3 ), 17.7% had moderate thrombocytopenia (20,000–50,000/mm 3 ), and 72.66% had mild thrombocytopenia (50,000–100,000/mm 3 ). Conclusion: A clinician should be alerted to the possibility of dengue infection if a patient has a fever accompanied by headache, retroorbital pain, an erythematous morbilliform rash, conjunctival suffusion, and itching in the palms and soles, as well as thrombocytopenia, leucopenia, and elevated liver transaminases.
Chikkaveeraiah et al. (Fri,) studied this question.