Symptoms and Psychosocial Factors on Quality of Life and Life Satisfaction in People with Parkinson’s Disease

Abstract Background Parkinson’s disease (PD) is one of the most common neurodegenerative diseases estimated to touch 9.3 million people worldwide by 2030. Motor and non-motor symptoms of PD have a debilitating effect on people with PD’s quality of life (QoL) and life satisfaction (LS). This study aims to explore the factors influencing people with PD’s lives in Ireland. Methods The sample comprised 827 participants, recruited through crowd-sourcing and snowball sampling. Participants were asked to complete a 30-minute survey online or on paper. The survey collected data on motor and non-motor symptoms, social connectedness, self-efficacy, stigma, QoL and LS. A series of linear and multiple regressions assessed the relationships between people with PD’s symptoms, psychosocial factors and their QoL and LS. Results Low self-efficacy and high levels of stigma were predictive of low QoL and LS, while low social connectedness was associated only with low QoL. Results showed reduced dexterity with hand/eye coordination, anxiety, apathy, pain and fatigue contributed to LS, whereas reduced dexterity with hand/eye coordination, shaking/tremors, stiffness of movement, freezing of gait, cognitive problems, hallucinations, apathy, compulsive behaviours, sleeping disorders, pain and urinary incontinence were contributors of QoL. Conclusion This study can provide insights into the factors influencing people with PD’s QoL and LS. Data can promote the development of therapeutic interventions targeting PD non-motor symptoms, which are often dismissed by clinicians. Finally, findings can inform the development of health and social policies and educate the general public to dissolve the stigma associated with PD.