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Background: The prevalence of diabetes mellitus has escalated globally, posing a significant public health challenge. While modern pharmacological interventions are available, there is growing interest in traditional medicinal agents as alternative or complementary treatments for diabetes. Aims and Objectives: This study aims to identify and evaluate the efficacy of conventional drugs in the treatment of diabetes, particularly focusing on herbal plants used in various traditional medicines. The primary objectives include identifying anti-diabetic herbal plants, evaluating their efficacy, and conducting docking studies to assess their anti-diabetic actions. Methodology: Relevant databases are searched to compile a comprehensive list of herbal plants with documented anti-diabetic properties. Information on each plant, including its botanical name, family, and components used, is collected. Evaluation of efficacy is conducted through a literature review and analysis of reported studies. Docking studies are performed to assess the molecular interactions between the active components of herbal plants and targets related to diabetes. Results and Discussion: The study has identified a range of traditional medicinal plants with potential anti-diabetic properties. Various botanical species from diverse families have been documented for their effectiveness in managing diabetes symptoms. The evaluation of efficacy suggests promising outcomes for several herbal plants in controlling blood sugar levels and improving metabolic functions. Docking studies reveal potential molecular mechanisms underlying the anti-diabetic actions of these plants, providing insights into their therapeutic effects. Conclusion: The findings highlight the potential of herbal plants as alternative or complementary treatments for diabetes. Further research and clinical trials are warranted to validate the efficacy and safety of these plants in diabetic management. Integrating traditional medicines into conventional diabetes care may offer additional therapeutic options and improve outcomes for patients.
Mehla et al. (Mon,) studied this question.