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This study identifies the HOXC11/PROM2/PI3K/AKT axis as a novel regulatory mechanism underlying ART-induced ferroptosis in ovarian cancer. Targeting the HOXC11/PROM2 axis may represent a promising therapeutic strategy for enhancing ferroptosis, offering new insights for the treatment of ovarian cancer.
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Jun Li
Xidian University
Feng Lu
North Sichuan Medical University
Yijun Yuan
North Sichuan Medical University
World Journal of Surgical Oncology
SHILAP Revista de lepidopterología
Soochow University
First Affiliated Hospital of Soochow University
North Sichuan Medical University
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Li et al. (Tue,) studied this question.
synapsesocial.com/papers/69dfedcc6324afb55d592fc4 — DOI: https://doi.org/10.1186/s12957-024-03544-w