Association of BRAF V600E Allele Frequency With Clinicopathologic Outcomes in Papillary Thyroid Cancer

Key Points

Key points are not available for this paper at this time.

Abstract

Higher AF was associated with gross ETE and increased recurrence risk. This may inform initial management in patients with PTC harboring an isolated BRAF V600E mutation.

Mark Helpful

Bookmark

Relay

Mark Helpful

Bookmark

Relay

Cite This Study

Schumm et al. (Thu,) studied this question.

synapsesocial.com/papers/69dff95bb28b234044e9c264 https://doi.org/https://doi.org/10.1210/clinem/dgae774

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Prognostic Value of Preoperative Molecular Testing and Implications for Initial Surgical Management in Thyroid Nodules Harboring Suspected (Bethesda V) or Known (Bethesda VI) Papillary Thyroid Cancer2023 · 37 citations
2Targeted Expression of BRAFV600E in Thyroid Cells of Transgenic Mice Results in Papillary Thyroid Cancers that Undergo Dedifferentiation2005 · 417 citations
3BRAF mutation in thyroid cancer2005 · 1,310 citations
4<i>BRAF</i> Gene Copy Number and Mutant Allele Frequency Correlate with Time to Progression in Metastatic Melanoma Patients Treated with MAPK Inhibitors2018 · 35 citations
5Systematic pan-cancer analysis of tumour purity2015 · 1,301 citations