Does the characterization of cardiac troponin fragment composition differentiate between acute injury and chronic disease?
Analyzing the composition of cardiac troponin fragments, specifically the proportion of long-cTnT ITC complex, may help differentiate acute myocardial injury from chronic disease.
Kinetic differences in multiple cTn forms contribute to the differentiation between acute injury and chronic disease, with a high proportion of long-cTnT ITC complex implying occurrence of acute injury.
Li et al. (Tue,) studied this question.
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