A STOP-Bang score ≥ 3, indicating increased risk of obstructive sleep apnea, was significantly associated with prediabetes meeting both FBG and HbA1c criteria (OR 1.06; 95% CI 1.01-1.12).
Cross-Sectional (n=10,131)
Is an increased risk of obstructive sleep apnea associated with a higher prevalence of prediabetes in adults without diabetes?
An increased risk of obstructive sleep apnea, as assessed by the STOP-Bang questionnaire, is significantly associated with prediabetes in the Korean general population, particularly among postmenopausal women.
Effect estimate: OR 1.06 (95% CI 1.01-1.12)
AIM: The association between obstructive sleep apnea (OSA) and prediabetes using the STOP-Bang questionnaire remains unknown. We aimed to investigate the prevalence of prediabetes among people based on their sleep apnea status. METHODS: This cross-sectional study included 10131 Korean adults without diabetes with information of STOP-Bang scores, drawn from the dataset of the Korea National Health and Nutrition Examination Survey 2019-2021. Prediabetes was defined in three subsets: only by fasting blood glucose (FBG) (FBG 100-125 mg/dL, HbA1c <5.7 %), only by HbA1c (FBG <100 mg/dL, HbA1c 5.7-6.4 %) or by both. We used multivariable logistic regression to assess the odds ratio (OR) and 95 % confidence intervals (CIs) for prediabetes. RESULTS: A total of 3828 subjects reported a STOP-Bang score of ≥ 3, which shows increased risk of OSA. Multivariable-adjusted OR (95 % CI) showed that a STOP-Bang score ≥ 3 was associated with prediabetes meeting both FBG and HbA1c criteria (OR 1.06; 95 % CI 1.01-1.12). This association was statistically significant among women, particularly postmenopausal women (OR 1.20, 95 % CI 1.10-1.30; OR 1.21, 95 % CI 1.11-1.32, respectively). CONCLUSION: In Korean general population, a significant correlation between higher OSA risk and prediabetes was observed, especially in postmenopausal women.
Um et al. (Sat,) conducted a cross-sectional in Prediabetes and Obstructive Sleep Apnea (n=10,131). High risk of OSA (STOP-Bang score ≥ 3) vs. Low risk of OSA (STOP-Bang score < 3) was evaluated on Prediabetes meeting both FBG and HbA1c criteria (OR 1.06, 95% CI 1.01-1.12). A STOP-Bang score ≥ 3, indicating increased risk of obstructive sleep apnea, was significantly associated with prediabetes meeting both FBG and HbA1c criteria (OR 1.06; 95% CI 1.01-1.12).