Modulating macrophage polarization towards the M2 phenotype, potentially through mitochondrial quality control, offers a promising therapeutic strategy to reduce rejection and improve cardiac graft survival.
The role and regulatory mechanisms of macrophage polarization in cardiac transplantation have gained significant attention. Macrophages can polarize into either the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype in... | Find, read and cite all the research you need on Tech Science Press
Chen et al. (Wed,) conducted a review in Cardiac transplantation. Macrophage polarization modulation was evaluated. Modulating macrophage polarization towards the M2 phenotype, potentially through mitochondrial quality control, offers a promising therapeutic strategy to reduce rejection and improve cardiac graft survival.
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