What question did this study set out to answer?

The aim is to identify challenges faced in conducting cancer clinical trials in low- and middle-income countries (LMICs).

April 28, 2025Open Access

Barriers and Opportunities for Cancer Clinical Trials in Low- and Middle-Income Countries

Key Points

The aim is to identify challenges faced in conducting cancer clinical trials in low- and middle-income countries (LMICs).
Survey conducted among clinicians experienced in clinical trials in LMICs.
Focused on challenges such as funding and workforce training.
Funding is identified as a major barrier to advancing clinical trials.
Lack of a well-trained research workforce hampers trial progression.

Abstract

This survey study of clinicians with clinical trial experience in LMICs suggests that adequate funding and a well-trained research workforce are 2 predominant challenges to advancing cancer therapeutic clinical trials in LMICs. Understanding these obstacles can inform efforts to support cancer clinical trials that better reflect worldwide needs and diversity by prioritizing and sustaining research led by LMIC investigators.

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Authors

Linsey Eldridge

National Cancer Institute

Nina R. Goodman

National Institutes of Health

A. Chtourou

National Institutes of Health

Journals

JAMA Network Open

Actions

Institutions

National Institutes of Health

National Cancer Institute

Indiana University – Purdue University Indianapolis

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Barriers and Opportunities for Cancer Clinical Trials in Low- and Middle-Income Countries

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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