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This study provides a comprehensive resource for understanding glioblastoma heterogeneity and spatial organization. GBmap and the TSS provide an integrative view of tumor architecture in GB, highlighting hypoxia-driven niches that may represent avenues for further investigation. Our resource can facilitate exploratory analyses and hypothesis generation to better understand disease progression.
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Cristian Ruiz-Moreno
Sergio Marco Salas
Erik Samuelsson
Neuro-Oncology
University College London
Radboud University Nijmegen
Uppsala University
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Ruiz-Moreno et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d9a26a00ab073a278370b3 — DOI: https://doi.org/10.1093/neuonc/noaf113