At-home physical activity metrics derived from digital health technologies, such as total non-sedentary activity time, were significantly higher in cancer patients with normal performance status compared to those with lower status (MD 1.54 hours, p=0.009).
Observational (n=62)
No
Do at-home physical activity and gait metrics measured by digital health technologies accurately reflect self-reported performance status in cancer patients?
Digital health technologies can objectively measure physical activity and gait in cancer patients, providing a more sensitive assessment of performance status than traditional in-clinic measures.
Mean Difference: 1.54 (95% CI 0.43–2.65)
p-value: p=0.009
Accurate assessment of performance status (PS) in oncology care is crucial for improving clinical decisions, therapy selection and anticipated risks of treatment toxicity. While physical function is traditionally assessed in the clinic, in-clinic instruments do not capture the full spectrum of daily functioning. Digital health technologies (DHTs) can address this limitation by passively monitoring patients in their daily environment. Our study showed at-home physical activity and gait metrics from DHTs were associated with self-reported PS in participants with cancer, and these metrics had greater discriminatory power than in-clinic measures among this cohort. The DHT-derived metrics were also significantly correlated with patient-reported-outcomes, and used of the devices was broadly acceptable to study participants. Therefore, integrating DHTs into oncological practice could significantly refine how PS is measured and utilized, ultimately enhancing treatment decision-making and clinical outcomes. (ClinicalTrials.gov NCT03952767).
Karahanoğlu et al. (Wed,) conducted a observational in Cancer (n=62). Home-based digital health technologies (accelerometers) vs. Self-reported KPS groups and healthy historical controls was evaluated on Total non-sedentary activity time difference between KPS 100 and KPS ≤70 (MD 1.54 hours, 95% CI 0.43-2.65, p=0.009). At-home physical activity metrics derived from digital health technologies, such as total non-sedentary activity time, were significantly higher in cancer patients with normal performance status compared to those with lower status (MD 1.54 hours, p=0.009).