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) was used to promote a green esterification of the lipoic acid with biobased alcohols to prepare circular biobased photocurable resins. The supported enzyme was employed for the preparation of a packed bed reactor and was easily recycled and reused to achieve the continuous production of lipoate-based photocurable resins with tuneable composition. Lastly, the environmental impact of the developed on-demand manufacturing process was compared to the previously reported esterification protocols through life cycle assessment, showing the effectiveness of continuous enzymatic flow synthesis in enhancing environmental performance across multiple areas, from human health to ecosystem impact and resources.
Moghal et al. (Fri,) studied this question.