A novel 3D motion-compensated free-breathing CMR sequence at 0.55 T enabled simultaneous high-resolution whole-heart bright- and black-blood imaging and accurate T2 mapping in a single 9-minute scan.
Does a novel 3D motion-compensated free-breathing sequence at 0.55 T provide accurate whole-heart assessment and T2 mapping in healthy subjects?
A novel 3D motion-compensated free-breathing CMR sequence at 0.55 T enables comprehensive whole-heart assessment and T2 mapping in under 9 minutes.
Introduction Conventional CMR exams for assessment of cardiac anatomy and tissue characterization require multiple sequential 2D acquisitions under breath-hold in different orientations, in addition to being limited to 1.5 T and 3 T. Methods In this study, we sought to develop a novel 3D motion-compensated free-breathing sequence for comprehensive high-resolution whole-heart assessment of cardiovascular anatomy via simultaneous bright- and black-blood imaging and co-registered T2 myocardial tissue quantification in a one-click scan at 0.55 T. Results Good agreement with a spin-echo reference sequence was found in the phantom for T2 mapping. In-vivo, the proposed research sequence was evaluated in 10 healthy subjects, providing great delineation of cardiac and vascular structures, good visibility of coronary arteries and accurate T2 parametric mapping in a clinically feasible time of less than 9 min.
Kokhanovskyi et al. (Thu,) conducted a other in Healthy (n=10). 3D whole-heart bright- and black-blood imaging with co-registered T2 mapping at 0.55 T vs. 2D spin-echo reference sequence (phantom) was evaluated on T2 mapping accuracy and anatomical image quality. A novel 3D motion-compensated free-breathing CMR sequence at 0.55 T enabled simultaneous high-resolution whole-heart bright- and black-blood imaging and accurate T2 mapping in a single 9-minute scan.