Supplementary Figure 5 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer | Synapse
July 15, 2025
Supplementary Figure 5 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
Key Points
MAIN FINDING: ISR pathway inhibition significantly affects immune cell populations in lung cancer.
KEY EVIDENCE: Data demonstrate changes in multiple immune checkpoints due to ISR pathway blockage.
APPROACH: The effect was evaluated using in vivo models to assess immune cell populations.
SIGNIFICANCE: This research highlights potential strategies for enhancing cancer immunotherapy by targeting the ISR pathway.
Abstract
Supplementary Figure 5 shows the effect of ISR pathway inhibition on immune cell populations in vivo.
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Cite This Study
Thomas-Jardin et al. (Tue,) studied this question.