What type of study is this?

September 10, 2025Open Access

Prescribing pattern and quality of life in patients of migraine at tertiary care teaching hospital

Key Points

Migraine significantly impacts quality of life, with 11.3% of patients facing severe disability according to MIDAS.
Among 150 patients, common treatments included NSAIDs like naproxen and TCAs like amitriptyline.
The study followed a one-year prospective observational approach at a tertiary care hospital in Gujarat.
Findings underscore the importance of effective management strategies to enhance patient outcomes and address psychological conditions.

Abstract

Background: Migraine, a prevalent and disabling neurological disorder, affects over a billion people globally, with a significant impact in India. Despite effective treatments, poor adherence and limited data on drug use and quality of life persist, especially in developing nations. Understanding these patterns is crucial for enhancing patient care, optimizing healthcare resources, and reducing the socioeconomic burden of migraine. Methods: This one-year prospective observational study was conducted at Shree Krishna Hospital, Gujarat, following ethical clearance. A total of 150 migraine patients diagnosed according to the ICHD-3 (International Classification of Headache Disorders, 3rd Edition) were enrolled. Data on demographics, treatment, and quality of life (via MIDAS Migraine Disability Assessment and MIBS-4 Migraine Interictal Burden Scale) were collected. Statistical analysis was conducted using STATA 14.2. Informed consent ensured participant confidentiality and adherence to research standards. Results: Among 150 migraine patients (74.7% female), most had low-frequency episodic migraine with moderate throbbing pain. NSAIDs (mainly naproxen) and TCAs (mainly amitriptyline) were widely used. MIDAS showed 11.3% had severe disability; MIBS-4 revealed 24% experienced severe interictal burden. Sleep disturbance, stress, and anxiety were common triggers, highlighting migraine's multifactorial impact on daily routine affecting quality of life. Conclusions: Although triptans have proven efficacy as acute treatment, their utilization remains limited. Quality of life assessments using MIDAS and MIBS-4 revealed significant disability, underscoring the need for enhanced management strategies targeting associated psychological conditions such as anxiety and depression. Optimizing prescription practices, improving patient education, and incorporating lifestyle modifications are crucial for effective long-term migraine management. These interventions promise improved patient outcomes.

Ask AI

Helpful

Bookmark

View Full Paper