Fatigue-resistant Hydrogels with Programmable Crystalline Domain Crosslinking Enabled by Coordinated Thermal-Solvent Strategy

Key Points

• Programmable crosslinking in hydrogels improves fatigue resistance and stability, crucial for ligament repair.
• The hydrogels exhibit enhanced flexibility and biocompatibility, with significant implications for artificial ligament use.
• Utilizing a coordinated thermal-solvent strategy, researchers effectively addressed hydrogel limitations in medical applications.
• Advancements in hydrogel design may enable better integration and performance in clinical ligament repair procedures.