Integrative Cardiovascular Pharmacology: Evaluating the Role of Taurine in Blood Pressure Regulation and Vascular Health

Taurine, a naturally occurring sulfur-containing amino acid, has gained attention for its potential to lower blood pressure and improve vascular health. Through multiple biological actions, such as regulating ion channels, enhancing antioxidant defenses, and modulating autonomic nervous system activity, taurine supports blood vessel function and reduces vascular stiffness. Evidence from randomized controlled trials and meta-analyses consistently shows that taurine supplementation, particularly at doses of 1.5 to 6 grams per day, leads to significant reductions in systolic and diastolic blood pressure, with the strongest effects observed in hypertensive and metabolically at-risk populations. Importantly, taurine is well tolerated with minimal adverse effects reported. This literature review synthesizes the current mechanistic and clinical evidence to evaluate taurine’s role as a safe and effective adjunct therapy for managing elevated blood pressure and improving cardiovascular outcomes.