Figure S3 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells

Key Points

• IGM-7354 promotes the expansion of nk cells and cd8+ t cells in vitro.
• Cytotoxicity is directed towards pd-l1 positive tumor cells, enhancing immune response.
• The method involves testing the immunocytokine's effects on immune cell populations.
• These findings indicate potential therapeutic applications for targeting tumor cells in cancer treatment.

Abstract