Diabetes mellitus (DM), a chronic metabolic disorder characterized by persistent hyperglycemia, has reached epidemic proportions globally. Conventional antidiabetic medications, while effective, are often limited by side effects, high costs, and reduced long-term efficacy. In contrast, medicinal plants have gained prominence for their bioactive phytoconstituents, affordability, and cultural relevance, especially in traditional healthcare systems. This review examines the nutritional benefits and antidiabetic mechanisms of medicinal plants, highlighting their roles in modulating blood glucose, enhancing insulin sensitivity, and mitigating diabetes-related complications. Bioactive compounds such as flavonoids, alkaloids, saponins, and polyphenols exhibit promising hypoglycemic effects through various biochemical pathways. Furthermore, many medicinal plants offer vital micronutrients and antioxidants that support overall metabolic health. Clinical and ethnobotanical evidence supports their potential as complementary therapies in diabetes management. As global interest in plant-based interventions increases, scientific validation and standardization of these natural remedies remain critical for integrating them into mainstream diabetic care. Keywords: Medicinal plants, Diabetes mellitus, Antidiabetic phytochemicals, Insulin sensitivity, Nutritional therapy, Flavonoids, Herbal medicine.
K. Agnes (Sun,) studied this question.
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