What type of study is this?

This is a In Vitro Study study (also classified as: Observational).

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September 10, 2025

Phytochemical and Pharmacological Evaluation of Cissus quadrangularis Linn

Key Points

Ethanol extract of cissus quadrangularis effectively reduces inflammation and promotes diuretic effects.
The study reports significant anti-inflammatory activity at a concentration of 500mg/ml against kidney stones.
Assessment involves in vitro diuretic tests using membrane stabilization and calcium oxalate methods.
The findings support traditional uses of cissus quadrangularis for bone-related conditions and kidney issues.

Abstract

Cissus quadrangularis L. is a perennial herb belongs to Vitaceae. Traditionally used in the treatment of bone related issues such as Fracture, Pain, Inflammation, Osteoporosis, Rheumatoid and Osteoarthritis. The Preliminary Phytochemical screening indicates the presence of alkaloids, flavonoids, tannins, saponins and phenolic compounds. The aim of this study is to investigate the Phytochemical and Pharmacological evaluation of ethanol extract of Cissus quadrangularis L. In vitroDiuretic and Anti- inflammatory activity performed by using calcium oxalate method and Membrane stabilization assay. The extract of various concentrations were tested using cystone as positive control and 500,250,100,50 and 10 µg/L concentrations were prepared and performed. Results showed that the ethanol extract at concentration 500mg/ml effective against the inflammation and proved to treat the kidney stones as a diuretic.

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