Introduction: Articaine-based local anesthetics are widely used for pain relief in children under 4 years of age. However, the use of these drugs is not regulated by official documents due to insufficient clinical data. Materials and methods: 126 children aged 1–4 years were examined for dental caries and its complications. A comparative clinical analysis of the effectiveness of local anesthetics based on Articaine and Lidocaine during dental treatment was performed. Results: A number of advantages of using Articaine in children 1–4 years old are shown, the pharmacodynamics and pharmacokinetics of this drug in comparison with analogues are considered. Practical tests based on the pain scale have been developed that make it easy to determine the degree of sensitivity to pain and the depth of local anesthesia at a dental appointment in children 1–4 years old. Conclusion: A higher efficiency of using Articaine-based drugs (Ultracaine, Articaine) as a local anesthetic at a dental appointment in children under 4 years of age compared with Lidocaine has been demonstrated.
Kudrin et al. (Thu,) studied this question.
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