August 13, 2025

RETRACTION: Blockade of High Mobility Group Box 1 Involved in the Protective of Curcumin on Myocardial Injury in Diabetes In Vivo and In Vitro

Key Points

Study results deemed unreliable due to data overlaps and previous publications, leading to retraction.
Key concerns include overlapping figures in data analysis, which ultimately question the validity of findings.
Retraction process involved the journal editor, various institutions, and the authors' lack of response to inquiries.
This incident emphasizes the importance of data integrity and the verification of research conclusions in published studies.

Abstract

RETRACTION : X. Yan , P. Xu , L. Zhou , J. Lu , H. Tang , Y. Zheng and H. Cao , “,” IUBMB Life 72 , no. ( 2020 ): 931 – 941 , https://doi.org/10.1002/iub.2226 . The above article, published online on 07 January 2020 in Wiley Online Library ( wileyonlinelibrary.com ), has been retracted by agreement between the journal Editor‐in‐Chief, Efstathios S. Gonos; the International Union of Biochemistry and Molecular Biology; and Wiley Periodicals LLC. The retraction has been agreed upon due to identified overlaps within the cell sections of the db/db panel in Figure 3b, as well as between the curcumin treated HMGB and PP65 panels in Figure 5b. Furthermore, elements of Figure 3b were previously published in other articles authored by different research groups. The authors did not respond to requests for comment and supporting data. As a result, the editors deem the article's results and conclusions unreliable and invalid. The authors did not respond to our notice of retraction.

Mark Helpful

Bookmark

Relay