What type of study is this?

This is a In Vitro Study study.

August 16, 2025Open Access

High‐Fidelity MRI Assessment of Cerebral Perfusion in Healthy Neonates Less Than 1 Week of Age

Key Points

Healthy neonates showed significant variations in cerebral perfusion measured by MRI, highlighting normal blood flow patterns.
Cerebral blood flow was analyzed using pCASL sequences, revealing differences across imaging techniques.
An advanced MRI methodology was employed to provide high-resolution assessment of cerebral perfusion in subjects under one week.
Results could enhance early detection approaches in this vulnerable population, supporting improved neonatal care.

Abstract

Journal of Magnetic Resonance ImagingVolume 62, Issue 3 p. spcone Cover ImageFree Access High-Fidelity MRI Assessment of Cerebral Perfusion in Healthy Neonates Less Than 1 Week of Age Zhiyi Hu BS, Zhiyi Hu BSSearch for more papers by this authorDengrong Jiang PhD, Dengrong Jiang PhDSearch for more papers by this authorJennifer Shepard CRNP, Jennifer Shepard CRNPSearch for more papers by this authorYuto Uchida MD, PhD, Yuto Uchida MD, PhDSearch for more papers by this authorKenichi Oishi MD, PhD, Kenichi Oishi MD, PhDSearch for more papers by this authorWen Shi BS, Wen Shi BSSearch for more papers by this authorPeiying Liu PhD, Peiying Liu PhDSearch for more papers by this authorDoris Lin MD, Doris Lin MDSearch for more papers by this authorVivek Yedavalli MD, Vivek Yedavalli MDSearch for more papers by this authorAylin Tekes MD, Aylin Tekes MDSearch for more papers by this authorWilliam Christopher Golden MD, William Christopher Golden MDSearch for more papers by this authorHanzhang Lu PhD, Hanzhang Lu PhDSearch for more papers by this author Zhiyi Hu BS, Zhiyi Hu BSSearch for more papers by this authorDengrong Jiang PhD, Dengrong Jiang PhDSearch for more papers by this authorJennifer Shepard CRNP, Jennifer Shepard CRNPSearch for more papers by this authorYuto Uchida MD, PhD, Yuto Uchida MD, PhDSearch for more papers by this authorKenichi Oishi MD, PhD, Kenichi Oishi MD, PhDSearch for more papers by this authorWen Shi BS, Wen Shi BSSearch for more papers by this authorPeiying Liu PhD, Peiying Liu PhDSearch for more papers by this authorDoris Lin MD, Doris Lin MDSearch for more papers by this authorVivek Yedavalli MD, Vivek Yedavalli MDSearch for more papers by this authorAylin Tekes MD, Aylin Tekes MDSearch for more papers by this authorWilliam Christopher Golden MD, William Christopher Golden MDSearch for more papers by this authorHanzhang Lu PhD, Hanzhang Lu PhDSearch for more papers by this author First published: 09 August 2025 https://doi.org/10.1002/jmri.70067Citations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky Graphical Abstract Comparison of cerebral blood flow (CBF) mapping results across different pseudo-continuous-arterial-spin-labeling (pCASL) sequences. (a) T2-weighted anatomical images in JHU-Neonate-Atlas space. (b) Group averaged CBF maps acquired with standard pCASL, large-vessel-suppression pCASL with crusher gradients applied in slice-selective (LVS-S-pCASL), readout (LVS-R-pCASL), and phase-encoding (LVS-P-pCASL) directions. (c) Group averaged temporal SD maps across measurements. Arrows indicate large vessel regions (i.e. Circle of Willis). Color bar indicates CBF and SD values in unit of mL/100 g/min. (737-748) Citing Literature Volume62, Issue3September 2025Page spcone RelatedInformation

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