Background: The role of adjunct medications, particularly the α2-agonist dexmedetomidine, to cause a reduction in the frequency as well as the intensity in the post-operative shivering in surgical patients, has been the topic of study for a considerable time. Objective: Our study aimed to investigate the effectiveness of dexmedetomidine, on reducing post-operative shivering in parturient undergoing after Cesarean section following neuraxial anesthesia. Methods: This double-blind randomized control trial was performed in anesthesia department in Liaquat National Hospital during January to August, 2024, involving pregnant females who exhibited shivering during Cesarean delivery under neuraxial anesthesia. Following the delivery, thirty patients in the study group received a single I/V infusion of 30mcg dexmedetomidine in 100ml of normal saline, while equal number of patients in the control group were given 100ml of normal saline only. Both allocation and randomization were done via a list generated by computer. The primary outcome was noticeable reduction in shivering following the administration of dexmedetomidine. Results: Out of 155 enrolled patients, sixty demonstrated shivering and were randomly assigned to study groups in 1:1 allocation. In the dexmedetomidine group, 3.3% of patients in comparison to 100% of patients in the control group, had no post-operative shivering. No events of bradycardia or hypertension were noted. Grade 3 sedation was observed in 4 cases in the dexmedetomidine group. Conclusion: In conclusion, a single IV infusion of 30mcg dexmedetomidine can effectively reduce events of post-operative shivering in parturients undergoing Cesarean section under neuraxial anesthesia.
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