What type of study is this?

This is a Literature Review study.

August 23, 2025Open Access

The Features of Advances and Challenges in Covid-19 Vaccine Development, Efficacy, Safety, and Global Deployment in General

Key Points

COVID-19 vaccines significantly contributed to pandemic control by offering essential efficacy and safety against severe disease, addressing global health needs.
The efficacy of various vaccine platforms, including mRNA and viral vector vaccines, remains critical in combating variants like Delta and Omicron, showcasing diverse immune responses.
Assessment involved a review of vaccine types, emphasizing safety profiles and the immunological responses necessary for robust protection against emerging variants.
Waning immunity and vaccine hesitancy pose challenges in sustaining pandemic control, indicating potential gaps in public health strategies and global deployment efforts.

Abstract

The rapid development and deployment of COVID-19 vaccines have marked a historic milestone in medical and pharmaceutical sciences, offering a critical tool to combat the global pandemic. The article synthesizes current knowledge on the diverse vaccine platforms, including mRNA, viral vector, protein subunit, and inactivated vaccines, highlighting their mechanisms, efficacy, and safety profiles. Were discussed the immunological responses elicited by vaccines, their performance against emerging variants such as Delta and Omicron, and the challenges posed by waning immunity and vaccine hesitancy.

Read Full Paperexternally

Mark Helpful

Bookmark

Relay

View Full Paper