Role of Diet and Gut Microbiome Composition in Women with Polycystic Ovarian Syndrome (Pcos): A Systematic Review

Polycystic ovarian syndrome (PCOS) is a condition with a range of symptoms, including chronic anovulation and hyperandrogenism. It is a hormonal condition that can affect the emotional and physical well-being of young women. Although the exact cause of PCOS is still unknown, one of the main characteristics of PCOS patients, who also have Acanthosis nigricans, is insulin resistance. Women with PCOS may benefit from dietary changes and lifestyle adjustments as first-line treatment. The symptoms of PCOS can be reduced by eating a healthy diet, maintaining a sufficient nutritional status, and engaging in regular exercise. Weight control and insulin regulation are the main goals of dietary therapies. Insulin resistance, immunological alterations, bile synthesis disruption, and ovarian dysfunction are consequences of disrupted gut microbiota. Databases including PubMed, Scopus, and Elsevier were searched for five years, from December 2018 to December 2023, to better understand the nutritional interventions and dietary changes made to PCOS patients to improve the makeup of their gut microbiome. The purpose of this systematic review was to understand the role of dietary modifications that seem to help improve Gut Health in PCOS.