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September 5, 2025Open Access

Expression of Concern Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2 cardiac myocytes

Key Points

The investigation raises issues about data integrity potentially affecting findings on hsp90's role in myocyte protection.
Concerns focus on images in Fig. 5, suggesting possible duplication of data from different experiments.
The editorial office has reached out to the authors for clarification, but has yet to receive a response.
This expression of concern aims to inform readers about integrity issues under investigation regarding the publication.

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the photos shown in Fig. 5B and D were apparently matching images, such that data which were intended to have shown the results of differently performed mitochondrial protection experiments appeared to have been derived from the same original source. The authors were contacted by the Editorial Office to offer an explanation for the apparent anomaly in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. International Journal of Molecular Medicine 28: 397‑403, 2011; DOI: 10.3892/ijmm.2011.682

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