40 Improving Access to Neurocognitive Assessment: Results of a Feasibility, Acceptability, and Validity Investigation of the Amsterdam Cognition Scan for Brain Tumor Patients

Abstract The Amsterdam Cognition Scan (ACS) is an online battery of ten cognitive tests that can be completed without supervision orsoftware downloads. The aim of our study was to evaluate the feasibility, acceptability, and validity of the ACS in English speaking brain tumor patients. Adults with primary brain tumors were recruited from the Princess Margaret Cancer Centre. Participants completed the ACS and corresponding traditional neuropsychological tests. We defined feasibility as 75% of participants being able to complete the ACS independently. Acceptability was evaluated through a satisfaction questionnaire and interview. Concurrent validity was evaluated using correlation coefficients (≥0.40 indicated acceptable validity) between the ACS and traditional tests. Fifty-one English speaking aduts completed the study (Mage=40.71 years; 51% male; diverse brain tumor types). 86% completed the ACS at home without assistance, 8% required mild technical assistance, and 6% required moderate assistance. Most participants rated the ACS as “very good” or “excellent” in terms of capturing cognitive problems (94%), time required to complete it (98%), and ease of use (96%). Correlations between the ACS and traditional tests ranged from 0.19 to 0.77, with acceptable concurrent validity on tests of memory (list learning, r=0.77, p0.01; delayed recall, ρ =0.70, p0.01), attention (digits forwards, r=0.542, p0.01; connect the dots, ρ=0.502, p0.01), executive functions (digits backward, r=0.410, p0.01; connect the dots II, ρ=0.741, p0.01) and motor dexterity (pegboard, ρ=0.644, p0.01). Findings suggest that the ACS is a feasible, acceptable, and valid way to measure neurocognition in English speaking brain tumor patients. The ACS may aid in improving access to neurocognitive assessments and facilitating more efficient gathering of neurocognitive data in this population.