Ventilator-associated pneumonia (VAP) remains a significant concern in intensive care units (ICUs) worldwide, particularly among patients requiring prolonged mechanical ventilation. This literature review synthesizes the existing body of research on VAP, its pathophysiology, prevalence, and associated microbial etiology, while emphasizing the impact of structured nursing interventions and ventilator care bundles (VCBs) in preventing its incidence. Textual and empirical evidence indicates that VAP prevention is multifactorial, involving adherence to aseptic techniques, proper hand hygiene, aspiration precautions, and educational interventions. Studies show that educational programs, compliance monitoring, and implementation of VCBs significantly reduce VAP rates, hospital stays, and associated costs. Training nurses through structured educational sessions and ensuring strict adherence to VCB protocols emerged as the most effective strategies for reducing VAP incidence. Future studies must focus on sustainability of compliance and the integration of evidence-based practices into routine ICU protocols to ensure long-term reduction in VAP-related morbidity and mortality. Keywords: Ventilator-associated pneumonia, nursing intervention, ventilator care bundle, ICU, compliance, education, infection control
Baria et al. (Sun,) studied this question.