Figure S4 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• Epithelial-to-mesenchymal transition was induced, highlighting the role of metabolic response in cancer progression.
• Key findings show that etomoxir and MCM treatment promote transition at the single-cell level in pancreatic cancer.
• Experimental approach included single-cell analysis methods to study the effects of microenvironmental cues.
• Understanding this pathway may lead to new therapeutic strategies targeting pancreatic cancer metastasis.