Figure S8 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• PPAR-δ activity drives significant lipidomic changes, facilitating metastatic behavior in pancreatic cancer.
• Lipid profiling revealed alterations linked to epithelial-mesenchymal transition due to PPAR-δ activation.
• The study highlights the role of PPAR-δ in regulating metabolic responses during cancer progression.
• Targeting PPAR-δ may provide a new avenue for therapeutic intervention in pancreatic cancer.