Supplementary Figure 20 from Microbiota Shape Metabolic and Immune Determinants of CAR-T Therapy and Correlate with Outcomes in Myeloma

Key Points

• Succinate levels correlate with therapy outcomes in multiple myeloma patients, highlighting metabolic influences.
• Stratification of stool and serum samples presents distinct patterns based on patient treatment results.
• Assessments focus on biomarkers like succinate, linked to immune responses impacting CAR-T therapy effectiveness.
• Illustrations suggest a link between microbiota, metabolic determinants, and immune factors in therapy outcomes.