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This is a Literature Review study.

September 10, 2025

Introduction to the update points of the 2025 European Association for the Study of Liver clinical practice guidelines for the management of chronic hepatitis B infection.

Key Points

The updated guidelines emphasize a comprehensive approach to managing chronic hepatitis B, covering various thematic chapters.
Key recommendations focus on treatment options and hepatocellular carcinoma surveillance for chronic hepatitis B patients.
The guidelines also address the management of special populations and prevention strategies for HBV reactivation.
Future research directions are outlined, indicating the need for ongoing advancements in chronic hepatitis B care.

Abstract

The European Association for the Study of Liver (EASL) on May 8, 2025, published the updated clinical practice guidelines for the management of chronic hepatitis B virus infection (HBV), which proposes a comprehensive, evidence-based approach to clinical practice. The recommendations are divided into ten thematic chapters, including diagnosis, treatment goals, treatment indications, treatment options, hepatocellular carcinoma surveillance, management of special populations, HBV reactivation prevention, post-transplant care, HBV prevention strategies, problems to be solved, and future research directions.

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