A Study of Thrombocytopenia in Pregnancy-Clinical Characteristics and Outcome in a Tertiary Care Centre

Thrombocytopenia is the second most common haematological finding in pregnancy next to anaemia. Platelet count below 1.5 lakh/cu mm. It carries a risk for both the mother and the fetus, associated with substantial maternal or neonatal morbidity and mortality. However, a specific therapy, if instituted promptly, improves the outcome for affected patients and their offspring. In patients in India, thrombocytopenia during pregnancy is an under explored condition. After taking consent from patients detailed history of period of gestation, high risk factors, past history, complications-during present and past pregnancy. History of petechiae, bruising, drug usage, viral infection, thrombocytopenia in previous pregnancy will be taken. General, systemic and obstetric examination will be done. All women platelet count estimation at the time of enrollment. Platelet count assessment will be done through automated blood count analyzer with routine antenatal hematological evaluation of the patient. In this study, there were 53.3% cases of mild thrombocytopenia, 33.4% of moderate thrombocytopenia and13.3%with severe thrombocytopenia. Gestational thrombocytopenia is the most common etiology .60 % of cases delivered at term, those delivered before term were mostly due to abruption or pregnancy was terminated for obstetric indications like severe preeclampsia, antepartum eclampsia, abruption or medical causes. Mode of delivery is not influenced. GT is the most common cause of thrombocytopenia during pregnancy (70%).