The study was conducted to compare the clinical differences in the onset, duration of action and complications of intrathecal isobaric Ropivacaine 0.5% Group A0.5 GROUP and intrathecal isobaric Ropivacaine 0.75% Group B0.75 GROUP in lower limb surgeries Materials and Methods: 60 patients belonging to ASA grade – I and Grade-II of both the sexes (each group 30 patients n=30) were randomly selected for the study. They were randomly allocated to receive either 3 mL glucose-free 0.5% (15 mg) or 0.75% (22.5 mg) isobaric ropivacaine in a non blinded fashion. The subarachnoid puncture was performed with a 25-gauge Quincke- needle at the L 3-L 4 interspace with the patients in the sitting position .The time of onset & duration of sensory and motor block, maximum no of dermatomes blocked and time taken for that, hemodynamic status, time for regression of sensory level to T10 dermatome, time of first request of analgesics and adverse effects were compared in both the groups. Conclusion: The subarachnoid injection of glucose-free isobaric Ropivacaine 0.5% and 0.75% solutions results in a variable spread of analgesia, accompanied by a good quality of motor block, Ropivacaine 0.75% produces a better quality of analgesia, longer duration of analgesia than the 0.5% solution.
samantula et al. (Thu,) studied this question.