AnaesthesiaEarly View Editorial The fewer the better or the more the merrier? The challenges of large research collaborations Britta S. von Ungern-Sternberg, Corresponding Author Britta S. von Ungern-Sternberg email protected orcid. org/0000-0002-8043-8541 @brittaₛleepydr Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Nedlands, Western Australia, Australia Anaesthesia and Pain Management Program, Institute for Paediatric Perioperative Excellence, The University of Western Australia, Perth, Western Australia, Australia Department of Anaesthesia and Pain Medicine, Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, Western Australia, Australia Perioperative Care Program, Perioperative Medicine Team, The Kids Research Institute Australia, Nedlands, Western Australia, Australia Correspondence to: Britta S. von Ungern-Sternberg Email: email protectedSearch for more papers by this authorJames Peyton, James Peyton Department of Anesthesia, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA, USA Department of Anaesthesia, Harvard Medical School, Boston, MA, USASearch for more papers by this authorClyde Matava, Clyde Matava Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada Department of Anesthesiology and Pain Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, CanadaSearch for more papers by this author Britta S. von Ungern-Sternberg, Corresponding Author Britta S. von Ungern-Sternberg email protected orcid. org/0000-0002-8043-8541 @brittaₛleepydr Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Nedlands, Western Australia, Australia Anaesthesia and Pain Management Program, Institute for Paediatric Perioperative Excellence, The University of Western Australia, Perth, Western Australia, Australia Department of Anaesthesia and Pain Medicine, Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, Western Australia, Australia Perioperative Care Program, Perioperative Medicine Team, The Kids Research Institute Australia, Nedlands, Western Australia, Australia Correspondence to: Britta S. von Ungern-Sternberg Email: email protectedSearch for more papers by this authorJames Peyton, James Peyton Department of Anesthesia, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA, USA Department of Anaesthesia, Harvard Medical School, Boston, MA, USASearch for more papers by this authorClyde Matava, Clyde Matava Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada Department of Anesthesiology and Pain Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, CanadaSearch for more papers by this author First published: 04 September 2025 https: //doi. org/10. 1111/anae. 16749Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more. Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky References 1Polaner DM, Taenzer AH, Walker BJ, et al. Pediatric Regional Anesthesia Network (PRAN): a multi-institutional study of the use and incidence of complications of pediatric regional anesthesia. Anesth Analg 2012; 115: 1353–1364. https: //doi. org/10. 1213/ane. 0b013e31825d9f4b. 10. 1213/ane. 0b013e31825d9f4b CAS PubMed Web of Science® Google Scholar 2Disma N, Veyckemans F, Virag K, et al. Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE). 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Ungern‐Sternberg et al. (Thu,) studied this question.