COPD is an irreversible, disabling respiratory disease that is characterised by great diagnostic complexity. COPD can be diagnosed early and accurately, but the current diagnosis tests, including PFT, have limited ability to determine structural changes in the lungs. HRCT has become a central imaging modality in visualizing the lung parenchyma: emphysema, broncho wall thickening, and air trapping. This study analysed the correlation between Scores of CT-derived lung attenuation and PFT Values of FEV1, FVC and FEV1/FVC in varying state of COPD. This study aimed to modify diagnostic model which included structural and functional evaluations. Atotal 70 patients of COPD ever treated at a tertiary care hospital were selected. In addition, lung quantification was done on HRCT to determine mean lung attenuation, airway wall thickness, and emphysema map. At the same time, PFTwas performed to assess FEV1, FVC, and the FEV1/FVC ratio in the cohort. Correlation among the values obtained with HRCT and PFT tests. These findings revealed a positive and powerful relationship between the HRCT measures and PFT indices particularly lung attenuation scores. Compared to patients with lesser degrees of airflow obstruction and normal or near normal FEV1 and FEV1/FVC, patients with greater extent of emphysema and lower luft LU attenuation values on HRCT scan, showed reduction in peripheral lung sparing. There was integration of HRCT with PFT may offer a logical evaluation approach to the severity of COPD, how it affects the structure and function of the lungs. Study concluded the clinical usefulness of the HRCTparameters and PFTin the diagnosis and staging of COPD.
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Shafket RasoolWani
Abhinav Jain
Infosys (India)
Kriti Malhotra
International Journal of Scientific Research
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RasoolWani et al. (Fri,) studied this question.
synapsesocial.com/papers/68c1956b9b7b07f3a0619a37 — DOI: https://doi.org/10.36106/ijsr/7614386
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