Motivation: The MULTIPLEX technique quantifies T1/T2*/PD/susceptibility maps in a single 3D scan, but dual TR, dual flip angle, and multi-echo acquisition strategies lead to long scan times. The CS-Wave method for 9-fold accelerated Wave-CAIPI faces issues like repeated iterations and limited information utilization, resulting in longer reconstruction times and reduced acceleration efficiency. Goal(s): Develop a fast, efficient reconstruction method to reduce time without losing quantification accuracy. Approach: This work introduces a deep Wave-ESPIRiT model to minimize iterations and maximize information utilization. Results: The DL-Wave-ESPIRiT reconstructs 9-fold accelerated Wave-CAIPI data in 30 seconds, achieving the quantification accuracy of a 4.5-minute CS-Wave reconstruction. Impact: The proposed DL-Wave-ESPIRiT method significantly reduces reconstruction time for accelerated MULTIPLEX imaging, achieving high accuracy in seconds instead of minutes. This advancement enhances clinical efficiency and enables faster, more effective imaging workflows.
Xue et al. (Tue,) studied this question.