Objectives: Cardiovascular diseases (CVD) are the leading cause of death and disability in the United States, with Asian Indians exhibiting a unique and heightened risk profile, marked by earlier onset and increased mortality. Indians often display significant dyslipidemia despite “healthy” body mass index (BMI) ranges, highlighting limitations of traditional risk factors. The objective of this retrospective, observational study was to assess the impact of race, sex, and age on lipid profile and BMI in Indians versus Whites, to guide more tailored CVD prevention and management strategies. Material and Methods: One hundred and ninety deidentified medical records were obtained from a cardiology clinic in New Jersey. The study stratified dyslipidemia and BMI differences by race, age, and sex to identify variations in cardiovascular risk profiles. Statistical analysis was performed using Statistical Package for the Social Sciences. Results: Indians showed significantly higher triglyceride levels despite lower BMI compared to Whites, with trends of elevated total cholesterol, low density lipoprotein, and non-high density lipoprotein cholesterol. Younger Indians (50 years). Females, irrespective of age, exhibited higher lipid profiles and increased CVD risk compared to males. Conclusion: Indians exhibit a pronounced risk for dyslipidemia, supporting the need for lower BMI cutoffs and ethnically tailored, early screening protocols, with a focus on younger adults and women, to reduce CVD risk.
Sharma et al. (Mon,) studied this question.
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