Motivation: While the brain's structural modules are the foundation of functional networks, the link between cortical gray matter diffusion properties and functional connectivity is still unclear. Goal(s): This study investigates the relationship between cortical microstructural diffusion and canonical brain functional networks. Approach: We used diffusion kurtosis imaging (DKI) to examine cortical microstructure in relation to high- and low-order brain networks. Results: Kurtosis diffusion in the cortex correlates with network hierarchy, showing distinct distributions between high- and low-order networks. DKI effectively maps cortical structure-function relationships. Impact: This study demonstrates that diffusion kurtosis imaging (DKI) effectively maps cortical microstructural properties, providing insights into brain network organization and offering potential for diagnosing and monitoring neurodegenerative conditions.
Wu et al. (Tue,) studied this question.
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