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This is a Experimental Study study.

September 17, 2025

Multi-shot Dual-Polarity GRAPPA for Nyquist Ghost and Fuzzy Ripple Artifact Correction of Echo-Planar Imaging

Key Points

Msh-DPG effectively corrects nyquist ghost artifacts, improving image quality in fMRI for better precision.
It significantly reduces fuzzy ripple artifacts compared to traditional correction techniques, enhancing visual fidelity.
The method maintains temporal resolution while correcting artifacts, critical for high-resolution fMRI analyses.
The approach supports enhanced stability for fMRI in ultra-high-field systems, vital for advanced neurological studies.

Abstract

Motivation: Nyquist ghost artifacts and fuzzy ripple artifacts are more pronounced in high-resolution fMRI in 7-Tesla, which may introduce bias into fMRI signal. Goal(s): The target of this study is to develop a technique for multi-shot-EPI-based sub-millimeter fMRI, which can correct the artifacts without reducing temporal resolution. Approach: We developed multi-shot dual-polarity GRAPPA (msh-DPG) which is a combination of DPG and traditional GRAPPA. Results: Msh-DPG can effectively correct the Nyquist ghosts and reduce the fuzzy ripple artifacts. It outperforms the linear phase correction method. Impact: The proposed method can correct or reduce two common artifacts in sub-millimeter fMRI without reducing the temporal resolution. It may help to improve the image quality and stability of high-resolution fMRI, especially in ultra-high-field systems.

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