What type of study is this?

This is a Quantitative Study study.

September 17, 2025

FOCUS-MUSE DWI in Primary Rectal Cancer: Comparison with FOCUS, MUSE, and Single-shot EPI DWI

Key Points

Focus-muse exhibited the highest contrast-to-noise-ratio in rectal cancer imaging, enhancing T staging accuracy.
The study involved 45 patients, measuring signal-to-noise-ratio and contrast-to-noise-ratio across four imaging techniques.
Focus-muse demonstrated superior image quality compared to focus, muse, and single-shot EPI, aiding tumor feature visibility.
These findings suggest that focus-muse DWI may improve the evaluation and management of rectal cancer in clinical practice.

Abstract

Motivation: DWI is important for rectal cancer (RC) assessment. FOCUS-MUSE is an advanced DWI technique which holds promise for superior image quality. However, its clinical application in primary RC remains uncertain. Goal(s): Compares the performance of FOCUS-MUSE with that of FOCUS, MUSE, and single-shot EPI DWI for primary RC assessment. Approach: 45 patients were enrolled, and each was imaged using the four sequences. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR), and T stage were assessed. Results: FOCUS-MUSE exhibited sufficient SNR and the highest CNR of RC lesion. It was also the best sequence to demonstrate subtle tumor feature for more accurate T staging of primary RC. Impact: Our study showed FOCUS-MUSE provided improved image quality of DWI for primary RC T staging. The application of FOCUS-MUSE DWI may be beneficial for evaluating and managing RC.

Mark Helpful

Bookmark

Relay