Abstract C134: Trends in prostate cancer disparities among diverse populations in Philadelphia

Abstract Background: Prostate cancer (PCa) is a leading cause of cancer morbidity and mortality in the US. There are profound differences in PCa outcomes by race/ethnicity and socioeconomic status. Over the last 15 years, PCa screening recommendations have changed, potentially influencing recent trends. To examine racial/ethnic differences in PCa incidence, stage at diagnosis, and mortality, we conducted statistical analyses focused on the diverse patient population of Philadelphia, Pennsylvania (PA). Methods: Early (stages I-II) and late-stage (stage IV and on) PCa incidence and mortality age-adjusted rates (per 100,000) from 2007-2022 were obtained from the PA Data Dissemination Informatics Exchange (EDDIE) for Philadelphia County. We calculated incidence rate ratios to measure disparity and compared percent change over time for patients of each major racial/ethnic group: Asian/Pacific Islander (API), Black, Hispanic, and White using PCa incidence rates. When used, “All Races” refers to Blacks, Whites, Asians, and Hispanics collective data. Disparity ratio measures compared the first year (2007 2025 Sep 18-21; Baltimore, MD. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2025;34(9 Suppl):Abstract nr C134.