Background: Urinary tract infections (UTIs) are among the most prevalent bacterial infections in children. Fever with or without focus is one type of clinical manifestation. Urinary tract anomalies are linked to high morbidity and death rates, so it's critical to diagnose and treat UTIs promptly. Isolating microbiological agents simplifies treatment. Purpose of this study was to identify the microbiological profile and antimicrobial susceptibility pattern that cause paediatric UTIs. Material and Method: 938 urine samples were taken from the suspected UTI cases. The semi-quantitative method known as the calibrated loop method was employed to isolate bacterial pathogens from urine specimens. The modified Kirby Bauer disc diffusion technique was used to conduct the antibiotic sensitivity test. Extended Spectrum Beta-Lactamase (ESBL) in GNB and Methicillin resistance in Staphylococcus was detected according to CLSI guidelines. Result: This study included 938 urine samples from clinically suspected UTI cases, with 38.2% showing substantial growth. The majority of 354 instances were reported in the 6-12 age-group. E. coli (29%) and Enterococcus (13.3%) were the most frequently identified Gram-negative and Gram-positive uropathogens. Nitrofurantoin was the most effective against Gram-negative organisms and Gram-positive organisms, followed by Vancomycin. 29.7% were ESBL producers. 28.1% were Methicillin resistant Staphylococcus. Conclusion: To optimize empirical therapy, it's important to assess the antibiotic sensitivity of UTI pathogens to commonly used antimicrobial drugs in specific location on a regular basis. Antibiotic resistance among paediatric urine culture isolates is on rise. We recommend empirical antibiotic selection based on local bacterial prevalence and sensitivities, rather than universal guidelines. Keywords: UTI, Pediatric population, ESBL, GNB, CLSI
Sethi et al. (Fri,) studied this question.