The application of Vision-Language Models (VLMs) in medicine is critically hampered by the scarcity of high-quality, expert-annotated data. Supervised Fine-Tuning (SFT) on existing datasets often leads to poor generalization on unseen modalities and tasks, while Reinforcement Learning (RL), a promising alternative, is stymied by the lack of reliable reward signals in this data-scarce domain. To break this impasse, we introduce Generative Reward Learning for Medical Reasoning (MedGR²), a novel framework that creates a self-improving virtuous cycle. MedGR² co-develops a data generator and a reward model, enabling the automated, continuous creation of high-quality, multi-modal medical data that serves as both a superior training source for SFT and RL. Our experiments demonstrate that SFT with MedGR²-produced data already surpasses baselines trained on large-scale, human-curated datasets. Crucially, when leveraging this data for RL via Group Relative Policy Optimization (GRPO), our model achieves state-of-the-art cross-modality and cross-task generalization, significantly outperforming specialized RL-based methods. Furthermore, our compact model, empowered by MedGR², achieves performance competitive with foundation models possessing over 10 times more parameters. MedGR² presents a new paradigm for data-efficient learning in high-stakes domains, transforming the problem from data scarcity to data generation and unlocking the full potential of RL for building truly generalizable medical AI.
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Wei Zhi
Jiayan Guo
Shangyang Li
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Zhi et al. (Thu,) studied this question.
www.synapsesocial.com/papers/68d6e0fc8b2b6861e4c3f45b — DOI: https://doi.org/10.48550/arxiv.2508.20549
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