The prevalence, risk factors, and in-hospital mortality of acute kidney injury according to KDIGO criteria in burn patients

Acute kidney injury (AKI) is a common complication in burn patients linked to higher mortality, but AKI defined by KDIGO criteria in this group is understudied. This retrospective study analyzed 592 burn patients with total body surface area (TBSA) ≥10% admitted between 1 January 2010 and 1 April 2024, examining AKI prevalence, risk factors, and in-hospital mortality via electronic records and laboratory results. Patients were grouped by AKI occurrence (AKI/non-AKI) and in-hospital survival (survivor/non-survivor), with logistic regression used to identify related factors. Results showed 29.1% AKI prevalence; in-hospital mortality was over 15 times higher in AKI patients (40.7% vs. 2.6%, p < 0.001). Independent AKI risk factors included age, admission hypotension/shock, full-thickness burn area, baseline sCr, sepsis, rhabdomyolysis, and DIC. AKI stages 2 and 3 independently raised in-hospital mortality, and AKI patients had significantly higher healthcare costs (p < 0.001). In summary, 29.1% of burn patients developed AKI, which correlated with increased in-hospital mortality.