Nanotechnology has emerged as a revolutionizing element in biomaterials research, significantly enhancing their functionality and versatility in medical applications from tissue engineering, drug delivery, regenerative medicine, to medical implants. Integration of nanomaterials in biomaterials has led to an enormous enhancement in biocompatibility, mechanical strength, drug release control, and bioactivity. The present review provides an exhaustive overview of the historical perspective, classification, and applications of nanomaterials in biomaterials research. It talks about how inorganic, organic, and hybrid nanomaterials are contributing to advancing biomedical applications, including their impact on scaffolds, nanoparticles for targeted drug delivery, and surface modification for implants. The paper also considers the current challenges associated with the use of nanomaterials, including biocompatibility, toxicity, scalability, and regulation. Finally, future research directions are proposed to drive the safety, functionality, and integration of nanotechnology in biomaterials, with possibilities for next-generation biomedical applications. This review aims to highlight the profound influence of nanotechnology on biomaterials and its potential to revolutionize healthcare. It explores the transformative impact of nanomaterials on biological applications and focuses on specific applications such as tissue engineering, drug delivery systems, diagnostic instruments, and regenerative medicine.
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Avinash Kumar Singh
Roshni Sharma
Vidya Spriha Kujur
Biomaterials connect.
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Singh et al. (Fri,) studied this question.
www.synapsesocial.com/papers/68d9052141e1c178a14f5145 — DOI: https://doi.org/10.69709/biomatc.2025.188313