Ultrasound-Triggered Prodrug Activation via Sonochemically Induced Cleavage of a 3,5-Dihydroxybenzyl Carbamate Scaffold

Key Points

• Ultrasound can effectively trigger prodrug activation, enhancing targeted drug release mechanisms.
• The method involves sonochemically induced cleavage of a carbamate scaffold to release active drugs.
• Utilizing ultrasound allows for precise control over drug release in deep tissues, reducing systemic side effects.
• This technique may pave the way for advanced clinical applications, emphasizing target-specific treatments.